Summary

Antibiotic susceptibility is essential in the prescription of empirical antibiotics before the results of cultures of wound samples are available [1]. For patients with chronic leg ulcers (CLU), increasing resistance to commonly used antibiotics has been observed. The aim of our study was to isolate the bacteria that infect CLU, determine their antimicrobial resistance profile and show how quickly patients develop resistance to the antibiotics used. Gram-negative bacteria (Proteus mirabilis and Pseudomonas aeruginosa) were more frequently associated with CLU than Gram-positive bacteria (Staphylococcus aureus). We observed that the antibiotics most likely to induce resistance in a short period of time for Gram-negative bacteria are cefepime and ceftazidime and for Gram-positive bacteria, fluoroquinolones, followed by aminoglycosides and macrolides, mostly in the urban area.