In this article we aim to briefly introduce some common issues in clinical medical practice, linked to cases diagnosed with terminal melanoma too late for therapy. Sometimes the major divergences of opinion are found between patient and their dermatologist. Consideration should be given to patient's rights to be informed , cared, counseled and treated even during terminal stages. But at the same time care must be taken to the doctor's attitude, the right and obligation to express their medical opinion and how he does this. Between doctor and patient there needs to be a professional relationship, flexible and humane.